Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Erectile dysfunction
ADR ID BADD_A05911
ADR Hierarchy
19      Psychiatric disorders
19.08      Sexual dysfunctions, disturbances and gender identity disorders
19.08.04      Sexual arousal disorders
19.08.04.001      Erectile dysfunction
21      Reproductive system and breast disorders
21.03      Sexual function and fertility disorders
21.03.01      Erection and ejaculation conditions and disorders
21.03.01.007      Erectile dysfunction
Description A disorder characterized by the persistent or recurrent inability to achieve or to maintain an erection during sexual activity. [CTCAE] The inability in the male to have a PENILE ERECTION due to psychological or organ dysfunction. [MeSH]
MedDRA Code 10061461
MeSH ID D007172; D007172; D007172
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Erectile disturbance | Erection decreased | Erection failure | Erection inadequate | Frigidity and impotence | Impotence | Impotent | Impotentia erigendi | Inability to maintain erection | Male erectile disorder | Male erectile disturbance due to general medical condition | Impotence aggravated | Erectile dysfunction NOS | Potency disturbance | Erectile dysfunction | Decreased frequency of erections | Erectile Dysfunction | Dysfunction, Erectile | Male Sexual Impotence | Impotence, Male Sexual | Sexual Impotence, Male | Male Impotence | Impotence, Male
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Prostaglandin G/H synthase 2O02768Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01350Maprotiline--
BADD_D01351Maprotiline hydrochloride--
BADD_D01352Maraviroc--
BADD_D01356Mecamylamine--
BADD_D01357Mecamylamine hydrochloride--
BADD_D01371Megestrol--
BADD_D01372Megestrol acetate--
BADD_D01378Memantine--
BADD_D01379Memantine hydrochloride--
BADD_D01382Mepenzolate--
BADD_D01383Mepenzolate bromide--
BADD_D01401Metformin--
BADD_D01405Methadone0.007292%
BADD_D01407Methamphetamine--
BADD_D01408Methamphetamine hydrochloride--
BADD_D01418Methotrexate--
BADD_D01419Methotrexate sodium--
BADD_D01425Methyldopa--
BADD_D01426Methyldopate hydrochloride--
BADD_D01431Methylphenidate0.000918%
BADD_D01437Methylscopolamine bromide--
BADD_D01442Metoclopramide--
BADD_D01443Metoclopramide hydrochloride--
BADD_D01444Metolazone--
BADD_D01445Metoprolol0.000062%
BADD_D01446Metoprolol succinate--
BADD_D01451Metyrosine--
BADD_D01452Mexiletine--
BADD_D01453Mexiletine hydrochloride--
BADD_D01454Mianserin--
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